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Senior Scientist 2 (12-month fixed term contract)

Posted 2 hours 4 minutes ago by BioLegend, Inc.

£80,000 - £100,000 Annual
Permanent
Full Time
Laboratory Jobs
Cambridgeshire, Cambridge, United Kingdom, CB1 0
Job Description
Senior Scientist 2- Bioproduction R&D- (12-month fixed-term contract)

Revvity's R&D Bioproduction department pioneers advanced expression platforms that power the manufacturing of next-generation biotherapeutics. Our portfolio includes specialized mammalian host cell lines, our innovative transposon-based expression system for rapid identification of high-expressing clones, and gene editing capabilities that enable custom cell line engineering. These technologies support both protein-based therapeutics and viral vector production, addressing the evolving needs of the biopharma industry.

Job summary

Join Revvity's Bioproduction R&D team as a Senior Scientist 2, where you'll drive innovation in our CHOSOURCE Expression platform. This is a hands-on, lab-based product development role focused on advancing CHO-based expression technologies for biotherapeutic production. You'll tackle real-world expression challenges, from optimizing productivity to enabling successful expression of diverse biologics and translate your findings into commercial products that empower biopharma customers worldwide.

Key responsibilities
  • Lead independent research projects to develop and validate new CHOSOURCE platform features for both stable and transient expression applications, from experimental design through execution, analysis, and troubleshooting
  • Mentor junior scientists through training, troubleshooting, and data review
  • Foster collaborative relationships within the team and across Revvity departments
  • Maintain comprehensive laboratory documentation and develop standard operating procedures
  • Present clear, concise data at both internal and external meetings
  • Support IP generation and regulatory documentation as needed for product commercialization
Essential Competencies & Requirements
  • Ph.D. in life science (molecular biology, biochemistry, cell biology or genetics) plus minimum 5 years of demonstrated experience in a relevant scientific discipline
  • In-depth knowledge of CHO cell line development, including stable pool generation, single cell cloning, and clone screening
  • Previous experience in transient expression systems and optimization would be a plus
  • Practical understanding of the challenges associated with expressing diverse biologics Advanced molecular biology skills, including expertise in diverse cloning methods (Gibson assembly, Golden Gate assembly), PCR, qPCR, and ddPCR
  • Experience applying Design of Experiment (DoE) methodologies to experimental design
  • Strong analytical mindset with ability to troubleshoot complex technical problems systematically
  • Proven ability to work effectively in cross-functional, fast-paced environments
  • Exceptional team collaboration skills with strong communication abilities and meticulous attention to detail
  • Demonstrated scientific curiosity with a proactive approach to knowledge development

Join our team and help shape the future of biotherapeutic production technologies at Revvity.

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