Senior Scientist 2 (12-month fixed term contract)
Posted 3 hours 1 minute ago by BioLegend, Inc.
Revvity's R&D Bioproduction department pioneers advanced expression platforms that power the manufacturing of next-generation biotherapeutics. Our portfolio includes specialized mammalian host cell lines, our innovative transposon-based expression system for rapid identification of high-expressing clones, and gene editing capabilities that enable custom cell line engineering. These technologies support both protein-based therapeutics and viral vector production, addressing the evolving needs of the biopharma industry.
Job summaryJoin Revvity's Bioproduction R&D team as a Senior Scientist 2, where you'll drive innovation in our CHOSOURCE Expression platform. This is a hands-on, lab-based product development role focused on advancing CHO-based expression technologies for biotherapeutic production. You'll tackle real-world expression challenges, from optimizing productivity to enabling successful expression of diverse biologics and translate your findings into commercial products that empower biopharma customers worldwide.
Key responsibilities- Lead independent research projects to develop and validate new CHOSOURCE platform features for both stable and transient expression applications, from experimental design through execution, analysis, and troubleshooting
- Mentor junior scientists through training, troubleshooting, and data review
- Foster collaborative relationships within the team and across Revvity departments
- Maintain comprehensive laboratory documentation and develop standard operating procedures
- Present clear, concise data at both internal and external meetings
- Support IP generation and regulatory documentation as needed for product commercialization
- Ph.D. in life science (molecular biology, biochemistry, cell biology or genetics) plus minimum 5 years of demonstrated experience in a relevant scientific discipline
- In-depth knowledge of CHO cell line development, including stable pool generation, single cell cloning, and clone screening
- Previous experience in transient expression systems and optimization would be a plus
- Practical understanding of the challenges associated with expressing diverse biologics Advanced molecular biology skills, including expertise in diverse cloning methods (Gibson assembly, Golden Gate assembly), PCR, qPCR, and ddPCR
- Experience applying Design of Experiment (DoE) methodologies to experimental design
- Strong analytical mindset with ability to troubleshoot complex technical problems systematically
- Proven ability to work effectively in cross-functional, fast-paced environments
- Exceptional team collaboration skills with strong communication abilities and meticulous attention to detail
- Demonstrated scientific curiosity with a proactive approach to knowledge development
Join our team and help shape the future of biotherapeutic production technologies at Revvity.