Research Intern - Process Development Team (NL)

Pushing the frontier of solid cancer therapy, Neogene Therapeutics is a global, clinical stage biotechnology company built on the premise of innovation and novel paradigm-changing science. Using tumor mutation profiles to engineer fully individualized T cell therapies, Neogene is bringing new hope to address the current limitations of treatments available today.

We offer the opportunity to join a highly dynamic biotech with locations in Amsterdam, Netherlands and in Santa Monica, CA. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies.

Neogene values pro-active team-players who pursue their goals with dedication, endurance, and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.

Are you a Bachelor's or Master's student who is interested in conducting research in an industrial setting? Apply for an internship at Neogene Therapeutics!

Position Summary

We are seeking a highly enthusiastic Research Intern to join our Process Development (PD) team. PD forms a crucial link between R&D and the final clinical cell product and in this highly exploratory field continued optimization of the cell product is further developed. This work will support the development of a clinical manufacturing process for engineered T cells with patient-derived neo-antigen specific TCRs. This entails optimizing and translating research protocols into clinical grade compliant procedures.

In this internship, you will learn about immunology principles and assays, gain experience with cell culturing, T cell gene editing tools (e.g. CRISPR-Cas9), bioprocess development, cGMP manufacturing and flow cytometry. You will report to a Scientist and be mentored by Research Associates in the PD group to experience first-hand what the day-to-day life of an industry researcher is. This is a full-time internship.

Essential Functions and Responsibilities

• Participate in the design, execution and support of laboratory studies for development, optimization, and manufacturing of genome engineered TCR T cell product.
• Execute and support analytical methods for process development studies.
• Support experimental designs, planning, execution, analysis, and reporting results of process development studies.
• Present obtained results in internal work discussions.
• Document laboratory procedures and results accurately in electronic laboratory journal.
• Perform general tasks relating to laboratory operations, such as storage of incoming shipments.

Required Skills/Abilities

• You will have the chance to improve your organizational and record keeping skills.
• You will have the opportunity to learn the interpersonal, verbal, and written communication skills necessary for a very collaborative environment.
• You are self-motivated and willing/able to work with accuracy, following protocols and documentation in a fast-paced company environment.

Education and Experience

• You are currently pursuing a bachelor's or master's degree in related scientific discipline.
• Previous experience with cell culture and flow cytometry is preferred.

DE&I Statement

Headline: We embrace our individual differences.

"Our mission is to build a workforce reflective of our communities to be receptive to patients' broad and unique perspectives, enabling us to empathize with their needs. Together, we strive to uphold a value system that promotes:

• Opportunities for continuous learning to drive behavioral change and to be respectful of other points of view
• A collaborative culture that leverages the diverse perspectives of employees and supports courage
• Zero tolerance for discrimination

We are committed to an emotionally and psychologically safe workplace that trusts employees to boldly explore innovative solutions. We recognize that intentionally embracing diversity at Neogene, empowers us to better relate to patients, and advance our mission to deliver cures where none exist."