Postdoctoral Research Assistant in R-loop biology

Postdoctoral Research Assistant in R-loop biology

Sir William Dunn School of Pathology, South Parks Road, Oxford

We are seeking to appoint a well-trained, enthusiastic and self-motivated scientist to join our team to investigate the mechanisms underlying the function of non-canonical RNA/DNA structures (R-loops) in health and diseases.

The post-holder will be responsible for managing their own academic research. The research project will involve a wide range of molecular biology and biochemical techniques, including RNA work, protein purification, mammalian cell culture, next generation sequencing genome-wide analyses (ChIP) and mass spectrometry. You will establish and optimise protocols, design and accurately execute experiments and contribute conceptually to the overall research programme.

The post-holder should hold, or be close to completion of, a PhD/DPhil in biochemistry, molecular/cell biology or genetics. You should have a good understanding of the principles of gene expression in higher eukaryotes as well as prior experience in biochemistry, molecular/cellular biology. You should have expertise in either molecular mechanisms of transcription, RNA biology, DNA damage or R-loop biology. Strong publication record (1st author publications), excellent organisational and communication skills are essential. Candidates with experience in genomic analyses, proteomic approaches, imaging analysis, iPS differentiation and bioinformatics would be especially welcome.

The post available as a fixed-term contract for 1 year.

The closing date for applications is midday on Friday 4 September 2026. Interviews will be held as soon as possible thereafter.

At the Dunn School we are committed to supporting the professional and career development of our postdocs and research staff. To help them thrive and achieve their ambitions, we have created a comprehensive range of opportunities and initiatives designed to provide an exceptional launchpad for their future careers.