Director, Onyx Enablement

Director, Onyx Enablement Business Introduction

At GSK, we want to supercharge our data capability to better understand our patients and accelerate our ability to discover vaccines and medicines. The Onyx Research Data Tech organization represents a major investment by GSK R&D and Digital & Tech, designed to deliver a step change in our ability to leverage data, knowledge, and prediction to find new medicines. We are a full stack shop consisting of product and tech delivery leadership, application and data engineering, infrastructure and DevOps, data/metadata/knowledge platforms, and AI/ML and analysis platforms, all geared toward:

• Building a next generation, metadata and automation driven data experience for GSK's scientists, engineers, and decision makers, increasing productivity and reducing time spent on "data mechanics"
• Providing best in class AI/ML and data analysis environments to accelerate our predictive capabilities and attract top tier talent
• Aggressively engineering our data at scale, as one unified asset, to unlock the value of our unique collection of data and predictions in real time
• Building data and prediction powered ways of working that accelerate GSK Research team's ability to find new drugs and vaccines

Position Summary

We are looking for a Director, Onyx Enablement who will report to the Senior Director, Onyx Portfolio Management in a Chief of Staff capacity to enable operational discipline within the Onyx organization. This role is for a credible leader who is expected to build strong relationships with the Onyx Engineering, Product, Program, and Quality leads, R&D stakeholders, and Enterprise partners such as Recruitment, Procurement, Finance, Compliance, RD&DT Portfolio, Real Estate & Facilities, and others. An excellent candidate should combine strong operational leadership with exceptional cross functional coordination skills, and be capable of building and running the core operational backbone of a complex engineering organization. This individual should have deep experience in procurement and vendor management, financial planning and forecasting, recruiting operations, and facilities coordination, with a demonstrated ability to establish scalable processes and governance structures. They must excel at navigating senior stakeholders, managing organizational cadences, and translating strategic objectives into actionable operational plans. The ideal candidate brings a track record of driving clarity, predictability, and efficiency across diverse teams, supported by strong analytical skills and a disciplined, metrics driven approach to organizational performance.

Key Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Develop and manage a comprehensive enablement and operational framework for Onyx, ensuring it is consistently applied across all Onyx teams.
• Partner with Procurement to drive procurement operations, including vendor selection, procurement strategy, contract execution, contract lifecycle management, and vendor performance tracking and reporting.
• Partner with Recruiting to manage hiring pipelines, coordinate interview logistics, accelerate onboarding, and ensure staffing plans align with organizational needs.
• Collaborate closely with Tech and R&D Finance to manage budgets, track and forecast spend, provide financial visibility, and ensure alignment to annual and quarterly budget targets (both OPEX and CAPEX).
• Coordinate with Real Estate and Facilities to manage Onyx's physical office footprint, including space allocation, operational readiness, and ongoing site support.
• Serve as the primary liaison to the central RDDT Portfolio team, managing intake, routing, prioritization, and follow up on organizational requests.
• Lead and orchestrate organization wide cadences and governance, including Townhalls, quarterly business reviews, stakeholder updates, and cross functional planning cycles.
• Establish and track organization level objectives, KPIs, and operational metrics; create reporting mechanisms and dashboards to measure operational performance, health, and delivery effectiveness.
• Identify and drive continuous improvement opportunities across operational workflows to enhance efficiency, predictability, and organizational scalability.

Why You?

We are building a team that values learning, collaboration and clear thinking. This role is hybrid with a mix of office and field work across the United Kingdom. We encourage people from all backgrounds to apply and to bring their unique perspectives. We welcome applications from those who will help us create an inclusive workplace.

Qualification, Skills & Experience

• Bachelor's degree or equivalent work experience
• Strong job related experience with an established track record of Enablement, Strategy or Operations for technology teams. Experience with an Engineering Organization is highly preferred.
• Strong communication and concise language skills. Self starter biased towards action. Proven ability to manage upwards and influence senior stakeholders.
• Change agent with strong leadership skills. Demonstrated ability to lead without authority, motivate, challenge the status quo, and deliver sustainable business improvements.
• Flexible thinking, ability to manage complexity and interpret strategy into pragmatic best practice deliverables.
• Familiarity with project and risk management principles.
• Ability to adapt, work under uncertainty and accommodate flexible work demands.
• Global perspective; cultural sensitivity.
• Ability to withstand pressure, self motivated with sense of urgency.

How to apply

We want to hear from you. Please submit your CV and a short cover letter describing a project where your enablement work improved performance. Tell us what you delivered, how you measured success and what you learned. We look forward to learning about you.

Closing Date: 7th January 2026

As we approach the holiday season, our recruitment team and hiring managers will have limited availability between now and early January. We encourage you to apply and we will review all applications, however response times will be longer than usual, and interviews will be scheduled after the New Year.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on or .

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.