Director - HEOR Statistics

• United States - Massachusetts - Cambridge
• United States - New York - Pearl River
• United States - Connecticut - Groton
• United States - Pennsylvania - Collegeville
• United States - New York - New York City

We're in relentless pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a healthier place. To fully realize Pfizer's purpose - Breakthroughs that change patients' lives - we have established a clear set of expectations regarding "what" we need to achieve for patients and "how" we will go about achieving those goals.

Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.

Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.

The Director, HEOR Statistics will provide statistical leadership and technical support for Pfizer projects involving health economics and outcomes research (HEOR). This is a quantitative-based position with limited administrative responsibilities. The candidate will work with teams in multiple therapeutic areas. The emphasis will be on sound statistical applications to patient-focused drug development and health technology assessment (HTA), with special focus on psychometrics and on health measurement science in the validation, design, analysis, interpretation, and communication of patient-reported outcomes and other clinical outcome assessments. The candidate is expected to develop highly effective collaborations with relevant stakeholders including those in HTA, Value & Evidence (including but not limited to its Patient-Centered Outcomes Assessment Group), Statistics, Clinical Pharmacology, Clinical Development, Medical Affairs, Epidemiology, Programming, and other groups contributing to HEOR analysis and strategy. The candidate is also expected to be highly proficient in HEOR methodology and strategy, including measurement science.

The primary responsibility and effort for the position is statistics-specific collaboration focusing on psychometrics and patient-reported outcomes and other clinical outcome assessments in oncology, inflammation & immunology, internal medicine, and vaccines. Responsibility extends to methodological research to improve the design, conduct, analysis, and interpretation of studies. In addition, given that the Statistical Research & Data Science Center, in which the position is housed, develops scientific collaborations to advance patient-centered development methodologies, the position may invite external publications and presentations (along with other professional activities).

The successful candidate will:

• Collaborate in the development and post-approval environment through consultation and implementation of statistical techniques related to HEOR based on state-of-the-science research.
• Enhance statistical expertise in value-based drug development among Pfizer HEOR scientists, statisticians, and clinicians through active engagement and leadership in research methodology and content-specific areas.

ROLE RESPONSIBILITIES

• Provide expert statistical support to HEOR leads in the validation, design, analysis, reporting, and interpretation of clinical outcome assessments (patient-reported, clinician-rated, observer-rated, and performance-based outcomes) and health economics in HEOR projects involving clinical trials and observational studies, including those in development supporting drug approval and reimbursement, HTA, as well as other post-approval activities, in order to inform decision-making and also to guide medical strategy and the scientific narrative through publications and external presentations.
• Partner with HEOR scientists, other HEOR statisticians, clinical statisticians, clinicians, statistical programmers, and others to develop and implement an effective plan to leverage HEOR data.
• Participate in HEOR regular meetings as needed and engage in proactive communications with project leads to better understand scientific and business needs.
• Provide computational and statistical advice on complex analytic issues supporting Pfizer's HEOR projects.
• Develop, implement, and promote methodologies based on state-of-the-science computing and statistical research and dissemination of the results both internally and externally.
• Provide a strong presence for Pfizer with HTA, regulatory and professional organizations to influence knowledge generation and content of regulatory guidelines to support the adaption of health economics and patient-reported and other clinical outcome assessments.
• Develop effective collaborations with relevant non-statistical researchers.
• Stay current with research on HEOR methodology and its applications pertinent to the Pfizer business needs.
• Be up to date on training and compliance with all Pfizer SOPs as required based on the assigned curriculum.

BASIC QUALIFICATIONS

• Ph.D. in biostatistics or related discipline.
• A minimum of 7 years of experience with psychometrics, health measurement scales, patient-reported outcomes, and other clinical outcome assessments, health economics, health technology assessment, and outcomes research methodology used in clinical trials and observational studies. Candidates with less work experience, or experience in other fields, will also be considered if they have exceptional methodology research credentials and potential.

PREFERRED QUALIFICATIONS

• Experience with advanced knowledge of econometrics, biometrics, longitudinal data analysis, missing data methods, multiple comparisons techniques, cost-effectiveness analysis, generalized linear models, meta-analysis, real-world data analysis, and conjoint analysis
• Proficient with subject matter content in at least one therapeutic area like oncology or inflammation
• Experience with different phases of drug development, from Phase 2 to Phase 4, and the associated regulatory and reimbursement involved
• Evidence of creative thought-leadership, professional presence, and scholarship through publications and presentations
• Effective verbal and written communication skills in relating to colleagues and associates both inside and outside the organization
• Broad-based understanding of statistical theory and its application

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
This is a site based Hybrid role

The Director, HEOR Statistics will provide statistical leadership and technical support for Pfizer projects involving health economics and outcomes research (HEOR). This is a quantitative-based position with limited administrative responsibilities. The candidate will work with teams in multiple therapeutic areas. The emphasis will be on sound statistical applications to patient-focused drug development and health technology assessment (HTA), with special focus on psychometrics and on health measurement science in the validation, design, analysis, interpretation, and communication of patient-reported outcomes and other clinical outcome assessments. The candidate is expected to develop highly effective collaborations with relevant stakeholders including those in HTA, Value & Evidence (including but not limited to its Patient-Centered Outcomes Assessment Group), Statistics, Clinical Pharmacology, Clinical Development, Medical Affairs, Epidemiology, Programming, and other groups contributing to HEOR analysis and strategy. The candidate is also expected to be highly proficient in HEOR methodology and strategy, including measurement science.

The primary responsibility and effort for the position is statistics-specific collaboration focusing on psychometrics and patient-reported outcomes and other clinical outcome assessments in oncology, inflammation & immunology, internal medicine, and vaccines. Responsibility extends to methodological research to improve the design, conduct, analysis, and interpretation of studies. In addition, given that the Statistical Research & Data Science Center, in which the position is housed, develops scientific collaborations to advance patient-centered development methodologies, the position may invite external publications and presentations (along with other professional activities).

The successful candidate will:

• Collaborate in the development and post-approval environment through consultation and implementation of statistical techniques related to HEOR based on state-of-the-science research.
• Enhance statistical expertise in value-based drug development among Pfizer HEOR scientists, statisticians, and clinicians through active engagement and leadership in research methodology and content-specific areas.

ROLE RESPONSIBILITIES

• Provide expert statistical support to HEOR leads in the validation, design, analysis, reporting, and interpretation of clinical outcome assessments (patient-reported, clinician-rated, observer-rated, and performance-based outcomes) and health economics in HEOR projects involving clinical trials and observational studies, including those in development supporting drug approval and reimbursement, HTA, as well as other post-approval activities, in order to inform decision-making and also to guide medical strategy and the scientific narrative through publications and external presentations.
• Partner with HEOR scientists . click apply for full job details