26.05.19 Research Fellow - School of Pharmacy

We are seeking a Research Fellow to lead the computational chemistry aspects of a BBSRC funded collaborative project Unlocking GPCR Signalling Bias: A Multiscale Approach to GPR84 and Beyond. The role holder will work closely with medicinal chemists at the University of Oxford and pharmacologists at the University of Glasgow, applying virtual screening, machine learning, AI driven generative chemistry, pharmacophore modelling, and molecular dynamics simulations to design novel GPR84 ligands with predictable signalling bias profiles.

Responsibilities

Lead the computational chemistry aspects of the project, collaborating with chemists and pharmacologists. Apply virtual screening, machine learning, AI driven generative chemistry, pharmacophore modelling, and molecular dynamics simulations to design novel GPR84 ligands.

Qualifications

• PhD in computational chemistry, computational biology, structural biology, biophysics, pharmacology or related discipline, to be obtained within 3 months of the start date.
• Significant experience in virtual screening and molecular docking.
• Experience with machine learning/AI approaches in drug discovery.
• Familiarity with generative chemistry platforms.
• Experience with pharmacophore modelling.
• Experience with molecular dynamics simulations.
• Strong scripting skills (Python, Bash).
• Experience with HPC environments.
• Knowledge of GPCR structure, function, and signalling pathways.

What We Offer

Beyond a competitive salary, the University offers an attractive benefits package including a holiday entitlement of up to 8.4 weeks a year, pension schemes and development opportunities. We support staff wellbeing with flexible working options, work life balance initiatives and support for physical and mental health. More detail is available at

Equality and Diversity

Queens University is committed to promoting equality of opportunity to all. We subscribe to Equality Charter Marks such as the Diversity Charter Mark NI and Athena Swan and have established staff networks such as iRise and PRISM that help progress equality and inclusion.

International Applicants

If you are an international applicant and do not already hold a visa that permits you to take up the role, please self assess using information available on the University website.

Contract

Fixed term contract posts are available for the stated period in the first instance but may be renewed or made permanent subject to availability of funding.

Application Process

To apply, visit