Research Scientist (Metaproteomics)

We are seeking a highly motivated Research Scientist in Metaproteomics to join a collaborative team focused on developing next generation computational methods for microbiome and metaproteomics data analysis. The role is primarily computational, involving the analysis and interpretation of large scale metaproteomics datasets, pipeline development and integration with other omics, and close collaboration with experimental researchers.

The post holder will work closely with a multidisciplinary group at the Quadram Institute, with access to state of the art metagenomics, metaproteomics and metabolomics infrastructure, and will design, implement and optimise computational pipelines to interpret microbiome function and its impact on host health, including AI assisted approaches.

Key Relationships

Work closely with Group Leader Kai Cheng, other group members, the Bioinformatics Team and the experimental metaproteomics team led by Prof. Daniel Figeys.

Responsibilities

• Develop, implement and optimise computational pipelines for metaproteomics data analysis.
• Integrate metaproteomics data with other omics (metagenomics, metabolomics) to generate biological insights.
• Apply and adapt computational and AI based methods for peptide/protein identification, quantification, functional annotation and biological discovery.
• Perform large scale data management, curation and computational analyses using high performance computing resources.
• Prepare results, reports and manuscripts for publication and present findings at scientific meetings.
• Assist in the preparation of research proposals and grant applications.
• Support the profile and reputation of the institute through engagement activities.
• Ensure research is conducted in accordance with best practices, scientific integrity and relevant policies.
• Contribute to the smooth running of the group, including mentoring and training activities.
• Carry out other duties commensurate with the nature of the post, as agreed with the line manager.

Education & Qualifications

• PhD in Proteomics, Bioinformatics, Computational Biology or a related field (essential).

Specialist Knowledge & Skills

• Strong understanding of proteomics or metaproteomics principles.
• Experience in metaproteomics or proteomics data analysis (DDA/DIA MS).
• Ability to interpret omics data in a biological context, particularly microbiome related questions.
• Proficiency in programming/scripting (Python, R, or Java).
• Experience with computational workflows for large scale omics data.
• Knowledge of statistical methods for high dimensional data.
• Experience with machine learning or AI approaches in biology.
• Demonstrated ability to analyse and interpret proteomics/metaproteomics data.
• Proven record in scientific writing and publication.
• Experience developing or applying computational workflows.
• Experience presenting research at scientific meetings.
• Contributions to collaborative or open source projects.
• Desirable: experience in multi omics data integration.
• Desirable: familiarity with microbiome or clinical datasets.
• Desirable: experience supervising students or providing technical training.

Interpersonal & Communication Skills

• Good interpersonal skills and ability to work as part of a team.
• Excellent communication skills, both written and oral.
• Strong organisational and time management skills.
• Ability to collaborate with internal and external stakeholders.
• Demonstrated ability to work independently, using initiative and applying problem solving skills.
• Ability to work to deadlines.

Additional Requirements

• Attention to detail.
• Promotes equality and values diversity.
• Commitment to scientific integrity and best practices.
• Willingness to embrace the expected values and behaviours of all staff at the Institute, ensuring a great place to work.
• Eligible to present a positive image of self and the Institute, promoting its international reputation and public engagement aims.
• Ability to maintain confidentiality and security of information where appropriate.
• Willingness to undertake occasional travel (national and international) related to collaborations and conferences.

Benefits & Salary

Salary on appointment will be within the range £37,500 to £45,350 per annum depending on qualifications and experience. This is a full time post for a 24 month contract.

The closing date for applications is 6 May 2026.

As a Disability Confident employer we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

The Quadram Institute Bioscience is a registered charity (No. ) and is an Equal Opportunities Employer.

This role meets the criteria for a visa application, and we encourage all qualified candidates to apply.