Postdoc Position: Cellular Biophysics

Are you curious about how chromatin influences the mechanical properties of the nucleus? And do you enjoy integrating biophysics, cell biology and quantitative imaging to answer fundamental questions in biology? Then this may be the opportunity you are looking for! Organising the genome while precisely regulating its function is one of the central challenges in biology. Cells continuously sense physical forces from their environment, which are transmitted to the nucleus and influence gene expression and cell differentiation. Alterations in cellular mechanobiology can contribute to disease, highlighting the importance of understanding these processes. Our lab investigates the biophysical mechanisms that shape chromatin organisation. In this project, you will apply a combination of biophysical and cell biology techniques to explore the relationship between mechanobiology and chromatin structure. The goal is to uncover how physical forces influence genome organisation and how misregulation may contribute to disease. We are seeking a scientist with a strong interest in chromatin biology who is eager to engage in multidisciplinary research. You will join the Chromatin Biophysics group at the Radboud Institute for Molecular Life Sciences under the supervision of Dr Jorine Eeftens. You will work closely with fellow group members in a multidisciplinary team, ranging from physicists to medical biologists. Our group maintains strong connections with the Institute for Molecules and Materials, providing ample opportunities for interdisciplinary collaboration within the institutes and with external partners. Profile You hold a PhD in biophysics, cell biology, mechanobiology or a related field. You are eager to expand your skills by working in an interdisciplinary field and team. You have excellent communication and writing skills (in English). It would be advantageous if you have experience with any of the following: optical tweezers, chromatin biology, mammalian cell culture and genetic perturbation techniques, live cell microscopy and quantitative image analysis. We offer We will give you a temporary employment contract of 2 years. Your salary within salary scale 10 depends on your previous education and number of years of (relevant) work experience. The amounts in the scale are based on a 38-hour working week. You will receive an 8% holiday allowance and an 8,3% end-of-year bonus. There may be an opportunity for Dual Career Coaching . The Dual Career Coaching assists your partner via support, tools, and resources to improve their chances of independently finding employment in the Netherlands. You will receive extra days off. With full-time employment, you can choose between 30 or 41 days of annual leave instead of the statutory 20. Additional Employment Conditions Work and science require good employment practices. This is reflected in Radboud University's primary and secondary employment conditions . You can make arrangements for the best possible work-life balance with flexible working hours, various leave arrangements and working from home. You are also able to compose part of your employment conditions yourself, for example, exchange income for extra leave days and receive a reimbursement for your sports subscription. And of course, we offer a good pension plan. You are given plenty of room and responsibility to develop your talents and realise your ambitions. Therefore, we provide various training and development schemes. We are The Radboud Institute for Molecular Life Sciences (RIMLS) is a leading interfaculty research institute of the faculties of Science (FNWI). Research areas of RIMLS include epigenetics, stem-cell and developmental biology, computational biology and biophysics. The central research theme is regulation of gene expression during development and in health and disease. RIMLS operates its own wet lab, microscopes and computational facilities. RIMLS currently has about 60 researchers, providing a vibrant and international working environment. The Eeftens team also has strong links with the Institute for Molecules and Materials (IMM), renowned for expertise in physical chemistry and soft matter, providing a synergistic multidisciplinary research environment. Practical information and applying You can apply only via the button below. Address your letter of application to Jorine Eeftens. In the application form, you will find which documents you need to include with your application. We look forward to receiving your application. The first interviews will take place on 12 January 2026. You will preferably start your employment as soon as possible. We can imagine you're curious about our application procedure . It describes what you can expect during the application procedure and how we handle your personal data and internal and external candidates. Do you already work at Radboud University and have questions about making an internal move? Learn more about internal applications .