Fleming Initiative Clinical Research Nurse

Fleming Initiative Clinical Research Nurse

Are you a skilled clinician ready to apply your nursing expertise to the frontline of medical research? Staphylococcus aureus is a leading cause of life-threatening infection worldwide, and with the rise of antimicrobial resistance (AMR), the need for new preventive strategies is urgent.

Main duties of the job

You willprovide high-quality clinical care and research delivery within a dedicatedmultidisciplinary team. Working closely with Dr Dinesh Aggarwal and ProfessorChris Chius experienced human challenge team, you will:

Champion the participant journey:Act as the primary point of contact for volunteers, managing their experiencefrom screening and recruitment through to enrolment and follow-up, ensuringthey feel informed, supported, and valued throughout.

Deliver clinical excellence: Assistwith the unique bacterial inoculation procedures (including suturing and biopsyassistance) and perform essential clinical skills, including phlebotomy andwound management, to the highest standards.

Ensure participant safety: Closelymonitor participants during their inpatient stay in our dedicated quarantinefacility, identifying and reporting adverse events promptly to ensure theirwellbeing.

Drive data collection: Collect awide range of microbiological and host samples and maintain accurate clinicaldocumentation and electronic data records in line with Good Clinical Practice(GCP) standards.

Collaborate across disciplines:Work as part of a supportive team of nurses, doctors, and scientists, assistingwith the wider portfolio of controlled human infection models when required toensure successful study delivery.

About us

Welcome to Imperial, a global top ten university where scientific imagination leads to world-changing impact.Join us and be part of something bigger. From global health to climate change, AI to business leadership, we navigate some of the world's toughest challenges. Whatever your role, your contribution will have a lasting impact.As a member of our vibrant community of 22,000 students and 8,000 staff, you'll collaborate with passionate minds across nine London campuses and a global network.This is your chance to help shape the future. We hope you'll join us at Imperial

Job responsibilities

Direct Clinical & Participant Care

Support smooth study delivery: recruit, screen and enrol participants into clinical studies of Staphylococcus aureus.

Act as a primary point of contact for study participants, providing clear guidance, support, and reassurance throughout their enrolment.

Take detailed clinical histories and collect highquality samples following enrolment including phlebotomy, microbiological sampling from various participant sites, and assist with surgical/dermatological procedures.

Guide participants through study procedures, ensuring excellent communication and participant experience.

Monitor participants during study visits and inpatient stays, ensuring their wellbeing and quickly escalating concerns to study physicians.

Identify, record, and report adverse events promptly to maintain participant safety.

Prepare for and undertake clinical study visits within the Imperial College Research Facility (ICRF).

Participant Recruitment & Study Delivery

• Recruit, screen, and enrol volunteers, ensuring all inclusion/exclusion criteria are met.
• Explain study procedures clearly, ensuring participants feel informed, comfortable, and valued.
• Support volunteers through every stage of the study journey - from first contact to followup.

Clinical Data & Documentation

• Maintain accurate, timely, and highquality clinical documentation in medical/research notes.
• Enter and manage clinical data and case report forms in line with GCP, GDPR, and data protection standards.
• Help maintain secure storage and backup of participant information in line with College, Sponsor and NHS policies.

Operational & Team Support

• Work closely with the Senior Research Nurse and Project Manager to ensure smooth day-to-day running of the research delivery, including development and refinement of study processes, SOPs and participant-focused pathways.
• Contribute to recruitment progress of participants, including recruitment strategies and communication with participants.
• Collaborate with the multidisciplinary team within Dr Aggarwals wider group and provide support to colleagues when needed.
• Collaborate with the research nursing team of Prof Chiu to support the wider portfolio of controlled human infection models when needed.

Training & Professional Development

• Keep up to date with clinical research standards, skin and soft tissue infection knowledge, and national regulations.
• Attend training, team meetings, and professional development opportunities.
• Maintain NMC registration and uphold all aspects of the Code of Professional Conduct.

Additional Duties

• Carry out administrative tasks appropriate for a Band 6 role.
• Adhere to College and NHS policies and maintain patient confidentiality at all times.
• As an Agenda for Change post, continue NHS career and pension progression while holding an honorary clinical contract aligned to your experience.

Clinical Responsibilities

This is an Agenda for Change post; as such, your NHS career progression and pension can continue. The post holder will hold an honorary clinical contract with the appropriate NHS Trust/s and will be expected to take clinical responsibilities appropriate to their level of experience and expertise.

Person Specification Qualifications

• Registration with the Nursing and Midwifery Council

Experience

• Minimum 2 years post experience in a relevant area.
• Evidence of up-to-date professional development.
• Previous wound management/closure experience.
• Independently able to collect blood and other samples.
• Experience in surgical theatre, dermatology, or infection prevention and control.
• Experience in clinical research and/or recruiting to studies.
• Experience handling, storing, or processing human/microbiological samples.
• Experience using electronic databases/eCRFs.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.