Chimiste

This is a contract of 1 year as Consultant (employee or freelance).

Job description:

• Development of an in-depth understanding of the chemistry relating to the postholder's projects and an awareness of chemical aspects of other projects within the group.
• Execution of preliminary literature surveys leading to the definition of experimental programs. Planning, preparation and implementation of experimental and/or scale-up studies using standard and specialized equipment and techniques (laboratory, kilo-lab & pilot plant). Initiation, monitoring and work-up of reactions as well as isolation and purifications of materials (laboratory, kilo-lab and pilot scale).
• Identification and definition of specific analytical tests in order to facilitate effective process development and ensure optimum product quality. Submission of materials for analysis and/or generation of analytical data using standard laboratory analyses. Interpretation of analytical results from these tests for laboratory, kilo-lab and pilot activities.
• Ensuring good record keeping with respect to all laboratory, kilo-laboratory and pilot plant activities, particularly regarding patentability & cGMP requirements.
• Preparation of detailed reports covering specific work programs on completion of the activities or whenever appropriate. Preparation of high-quality documentation in support of potential patent applications and other publications as requested.

Requirements:

• Strong knowledge in general organic chemistry both theoretical and practical; chromatography (HPLC/UPLC/GC) and characterization techniques (UV; PAT; NMR and MS spectrometry); Automatized equipment, typical lab equipment.
• Ability to participate in the route selection / process identification and optimization, robustness studies, QBD development of the different compounds in development.
• Experience in ensuring that all developed processes can be scaled up to a 60 L reactor and perform the syntheses at this scale in the Kilolab.
• Experience in transferring to the Pilot Plant.
• Understanding of regulatory and GMP environments

Offer:

• Group insurance
• Hospitalisation insurance
• Meal vouchers of 7 euros gross per working day
• Reimbursement km or company car
• Monthly allowance (80 euros net per month)
• A 13th month
• Training
• Etc.