Associate Director Supply Chain International

Madrigal is a biopharmaceutical company pursuing novel therapeutics for non-alcoholic steatohepatitis (NASH), also known as metabolic dysfunction associated steatohepatitis (MASH). Our first therapy was granted accelerated approval by the U.S. Food and Drug Administration (FDA) for the treatment of adults with NASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) and is being studied in a Phase 3 trial for the treatment of NASH with compensated cirrhosis.

Position Title: Associate Director Supply Chain International

Department: International Supply Chain

Reporting to: Executive Director, Supply Chain

Location: Zug, Switzerland or Amsterdam, the Netherlands (please indicate your preferred location in your application)

Position Overview:

The Regional Supply Chain Lead is responsible for managing, coordinating, and optimizing supply chain activities across multiple countries within their region. This role focuses on ensuring timely and compliant product launches, efficient distribution management, and seamless collaboration with affiliates, commercial teams, and third-party logistics (3PL) providers.

Key Responsibilities:

1. Strategic Design and Implementation:

• Contribute to the development of the regional Supply Chain strategy and ensure effective execution.

2. Supply and Inventory Planning:

• Develop and oversee the execution of launch plans in collaboration with different stakeholders including (a.o. affiliates, regional teams, regulatory, quality and finance)
• Implement and manage Life Cycle Management processes to ensure supply continuity.

3. 3PL Management:

• Select, implement, and manage regional 3PL partners, ensuring high quality, compliance, and optimal service levels.

4. Cross-Functional Collaboration:

• Act as a primary supply chain liaison with commercial teams, country-level GMs, and global functions such as Global Supply Chain, Regulatory, and Quality Assurance.
• Ensure processes, systems, and requirements are harmonized and clearly aligned.

5. Operational Readiness and Execution:

• Prepare and execute comprehensive operational readiness plans, ensuring supply chain infrastructure, processes, and systems support the regional launch strategy.
• Manage launch readiness checklists, timelines, and risk mitigation plans.

6. Serialization and Artwork:

• Coordinate closely with regulatory and supply teams to ensure artwork and serialization requirements (e.g., EU FMD, EMVO/NMVO) are fully understood and properly implemented.
• Serve as the primary contact for serialization-related matters within the region.

7. Compliance:

• Ensure regional supply chain operations comply fully with GMP/GDP regulations and internal policies.
• Manage regional deviation and change control processes.

8. Distributor and Wholesale Selection:

• Participate in and lead distributor and wholesale selection processes, supporting negotiation and implementation of supply agreements.
• Develop and implement effective supply processes with selected partners, as dictated by commercial strategy.

9. Performance Monitoring and Continuous Improvement:

• Monitor and report key performance indicators (KPIs), including service levels, inventory accuracy, OTIF delivery, and overall supply chain effectiveness.
• Drive continuous improvement initiatives to enhance efficiency, compliance, and responsiveness of the regional supply chain.

Qualifications and Experience:

• Bachelor's degree (Master's preferred) in Supply Chain Management, Business, Engineering, or related field.
• 8-10+ years' supply chain experience in pharmaceuticals or biotech, with significant experience in regional or multi-country supply chain management.
• Proven track record in product launch management within the EU, ideally involving supply and demand planning, artwork requirements, serialization, and 3PL preparations.
• Experience in 3PL and Wholesaler management within the EU, including selection, implementation, order-to-cash, and distribution.
• Understanding of GDP/GMP compliance, serialization (FMD), and other relevant regulatory requirements. Ideally including licensing projects for WDA/MIA/API Registration
• Ideally prior experience building infrastructure and processes from scratch in startup environments; if not, must have experience with implementation of processes and systems.
• Experience working closely with commercial teams, regulatory, and quality assurance functions, balancing corporate and regional perspectives.
• Ideally experienced in both larger pharma and smaller company environments.

Skills and Attributes:

• Excellent interpersonal, communication, and stakeholder management skills.
• Strong project management and execution capabilities, with a hands-on mentality and proactive approach to driving results.
• Ability to operate independently with minimal supervision and adapt quickly to evolving challenges.
• Must be flexible and comfortable dealing with high degrees of uncertainty and ambiguity.
• Strong analytical and problem-solving abilities, with a proactive and hands-on approach.
• High potential with demonstrated capability to lead small or limited teams effectively.

Additional Information

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.