Associate Director, Oncology Translational Medicine
Posted 18 hours 22 minutes ago by Ccrps
Are you interested in developing, integrating, and implementing innovative biomarker strategies for Oncology clinical development programs, including validation and integration of biomarker assays into clinical trials? If so, the Clinical Biomarker Lead role within Oncology Translational Medicine could be an ideal opportunity to explore.
Responsibilities- Lead and/or contribute to clinical asset biomarker strategy for early-stage oncology programs to generate data that informs on target engagement, pharmacodynamics, mechanism of action and patient selection.
- Represent Oncology Translational Medicine Biomarker team at Clinical trial study teams (CST) and Biomarker/OTM Matrix teams. Establish clear decision making criteria to enable biomarker-informed clinical decisions.
- Provide input to clinical teams on biomarker related elements of clinical protocols, lab manuals and consent forms.
- Develop and implement novel biomarker assays.
- Provide scientific expertise and technical guidance to enable timely biomarker sample collection.
- Execute sample testing plan and deliver high quality biomarker data packages to inform clinical development and regulatory strategy.
- Point of contact for resolving study biomarker issues.
- Collaborate with clinical operations and sample management to ensure biomarker testing and data generation.
- Align with the companion diagnostics team to deliver novel precision medicine approaches to select patients for treatment.
- Serve as a point of contact for external vendors and collaborators in support of data generation.
- Provide frequent project status updates related to biomarker deliverables.
- Ph.D. or equivalent with 2+ years or M.Sc with 5+ years of relevant experience in biotechnology or pharmaceutical industry setting in the application of biomarkers in clinical trials preferably in oncology biomarker development.
- 2+ years' experience in conducting biomarker analyses on various clinical sample types and working as part of a clinical study team.
- Experience in high impact contributions to biomarker discovery and/or assay development.
- Experience working in a matrixed, multidisciplinary team environment.
- Deep understanding and experience working in Oncology biomarker strategies and application to clinical trials, preferably in ADC and other novel modalities.
- Up to date knowledge and deep understanding of major biomarker assay technologies and platforms.
- Demonstrates strong knowledge of translational models and data, with a focus on clinical relevance.
- Experience in Correlative Science.
- Effective verbal and written communication skills relating to key stakeholders including colleagues, associates, and senior leaders both inside and outside of GSK.
- Experience in managing research collaborations, contract laboratories and budgets.
- Demonstrated scientific capability as evidenced by publications, research reports, and external presentations.
- Flexibility to work on multiple projects as the portfolio evolves over time.
- Knowledge and track record of working to GCP principles.
- Having a strong sense of urgency and excellent skills in prioritization, planning as well as timely execution in a very fast paced environment.
- Strong interpersonal skills and ability to thrive in a matrix environment.
If you are ready to use your translational expertise to make a tangible difference in clinical development, we would love to hear from you. Please submit your CV and a brief cover letter describing a recent translational challenge you led and the outcome. We welcome applicants from all backgrounds and are committed to inclusion.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.